| Maneater |
PS5 | Tripwire Interactive | Action, Adventure, and RPG & JRPG | | 2021-01-13 |
| Killer Queen Black |
PC: Steam | Liquid Bit | Action, Arcade & Casual, Multiplayer (Online), and Strategy | | 2021-01-15 |
| Please Wake Up |
PC: Steam | CLU Entertainment | Psychological Horror | | 2021-02-01 |
| Control |
Sony PS4 | 505 Games | Action and Adventure | | 2021-02-03 |
| Concrete Genie |
Sony PS4 | Sony | Action and Adventure | | 2021-02-03 |
| Resident Evil 2 |
PC: Steam | Capcom | Survival Horror & Horror | Resident Evil | 2021-02-04 |
| Shining Resonance Refrain |
PC: Steam | Sega of America | RPG & JRPG | | 2021-02-28 |
| Remnant: From the Ashes |
Sony PS4 | Perfect World Entertainment | Action and Survival | | 2021-03-02 |
| Call of Duty: Black Ops Cold War |
Sony PS4 | Activision | First-Person Shooter, Multiplayer (Local), and Multiplayer (Online) | Call of Duty | 2021-03-03 |
| Spirit Hunter: Death Mark |
PC: Steam | Aksys Games | Survival Horror & Horror and Visual Novel | | 2021-03-16 |
| Stardew Valley |
PC: Steam | ConcernedApe | Open-ended, RPG & JRPG, and Sim / Simulation | | 2021-03-27 |
| The Ambassador: Fractured Timelines |
PC: Steam | The Quantum Astrophysicists Guild | Action, Adventure, and RPG & JRPG | | 2021-03-27 |
| Ultimate Chicken Horse |
PC: Steam | Clever Endeavour Games | Multiplayer (Online) and Platformer | | 2021-03-27 |
| Resident Evil 7 Biohazard |
PC: Steam | Capcom | Survival Horror & Horror | Resident Evil | 2021-04-14 |
| Zombie Army 4: Dead War |
Sony PS4 | Rebellion | Action, Multiplayer (Online), Shooter, and Survival Horror & Horror | Zombie Army | 2021-04-17 |
| The Witness |
Sony PS4 | Thekla | Adventure and Puzzle | | 2021-04-21 |
| Quiplash |
PC: Steam | Jackbox Games | Arcade & Casual and Multiplayer (Online) | | 2021-04-22 |
| Everybody's Golf |
Sony PS4 | Sony | Multiplayer (Online) and Sports | | 2021-06-27 |
| PowerWash Simulator |
PC: Steam | Square Enix | Open-ended and Sim / Simulation | | 2021-06-29 |
| Call of Duty: Black Ops 4 |
Sony PS4 | Activision | Action, First-Person Shooter, and Multiplayer (Online) | Call of Duty | 2021-07-07 |
| A Plague Tale: Innocence |
PS5 | Focus Home Interactive / Focus Entertainment | Action and Adventure | | 2021-07-07 |
| Never Alone (Kisima Ingitchuna) |
PC: Steam | E-Line Media | Action and Adventure | | 2021-07-07 |
| SOMA |
PC: Steam | Frictional Games | Action, Adventure, and Survival Horror & Horror | | 2021-07-07 |
| Downfall |
PC: Steam | Screen 7 | Adventure and Survival Horror & Horror | | 2021-07-07 |
| Seasons after Fall |
PC: Steam | Focus Home Interactive / Focus Entertainment | Adventure and Platformer | | 2021-07-07 |
| The Light Remake |
PC: Steam | Hockob Cepren | Adventure and Walking Simulator | | 2021-07-07 |
| Paradise Killer |
PC: Steam | Fellow Traveller | Adventure and Puzzle | | 2021-07-09 |
| Song of Horror: Complete Edition |
PC: Steam | Raiser Games | Adventure and Survival Horror & Horror | | 2021-07-28 |
| Tomb Raider: Anniversary |
PC: Steam | Square Enix | Action and Adventure | Tomb Raider | 2021-08-16 |
| Hitman 2 |
Sony PS4 | IO Interactive | Action and Adventure | Hitman | 2021-09-09 |
| Not for Broadcast |
PC: Steam | tinyBuild | Point & Click and Sim / Simulation | | 2021-09-10 |
| Donut County |
PC: Steam | Annapurna Interactive | Adventure and Arcade & Casual | | 2021-09-11 |
| Curse That Magic Cat! |
PC: Steam | SMU Guildhall | Arcade & Casual and Sim / Simulation | | 2021-09-12 |
| Boyfriend Dungeon |
PC: Steam | Kitfox Games | RPG & JRPG and Sim / Simulation | | 2021-09-12 |
| If On A Winter's Night, Four Travelers |
PC: Steam | Dead Idle Games | Adventure, Point & Click, and Psychological Horror | | 2021-09-23 |
| Ori and the Will of the Wisps |
PC: Steam | Xbox Game Studios | Action and Platformer | Ori | 2021-10-17 |
| Among the Sleep: Enhanced Edition |
PC: Epic Games | Krillbite Studio | Adventure and Psychological Horror | | 2021-10-26 |
| The Jackbox Party Pack 3 |
PC: Steam | Jackbox Games | Arcade & Casual, Board & Family, and Multiplayer (Online) | The Jackbox Party Pack | 2021-11-01 |
| Kingdoms of Amalur: Re-Reckoning |
Sony PS4 | THQ Nordic | Action, Adventure, and RPG & JRPG | | 2021-11-10 |
| Prototype Mansion - Used No Cover |
PC: Steam | Jupiter Lighthouse Games | Survival Horror & Horror | | 2021-11-24 |
| Outlast |
PC: Steam | Red Barrels | Survival Horror & Horror | Outlast | 2021-11-24 |
| Outlast 2 |
PC: Steam | Red Barrels | Survival Horror & Horror | Outlast | 2021-11-24 |
| Mass Effect Legendary Edition |
PC: Steam | Electronic Arts | Action, RPG & JRPG, and Shooter | Mass Effect | 2021-11-25 |
| while True: learn() |
PC: Epic Games | Luden.io | Puzzle and Sim / Simulation | | 2021-12-05 |
| Sakuna: Of Rice and Ruin |
Sony PS4 | XSeed Games | Action, RPG & JRPG, and Sim / Simulation | | 2021-12-09 |
| Purrfect Date |
PC: Steam | Bossa Studios | Dating Sim and Visual Novel | | 2021-12-11 |
| The Forest |
PC: Steam | Endnight Games | Sim / Simulation and Survival Horror & Horror | The Forest | 2021-12-22 |
| Nanotale: Typing Chronicles |
PC: Steam | Fishing Cactus | Adventure and RPG & JRPG | | 2021-12-22 |
| A Little Lily Princess |
PC: Steam | Hanako Games | Sim / Simulation and Visual Novel | | 2021-12-22 |
| The Dark Pictures Anthology: House of Ashes |
PC: Steam | Bandai Namco | Adventure and Survival Horror & Horror | The Dark Pictures Anthology | 2021-12-25 |
| Poppy Playtime, Chapter 1 |
PC: Steam | MOB Games | Puzzle and Survival Horror & Horror | Poppy Playtime | 2021-12-29 |
| Papers, Please |
PC: Steam | 3909 | Puzzle and Sim / Simulation | | 2021-12-29 |
| Let's Build a Zoo |
PC: Steam | No More Robots | Sim / Simulation and Strategy | | 2021-12-29 |
| The Legend of Heroes: Trails in the Sky |
PC: Steam | XSeed Games | RPG & JRPG | Trails | 2021-12-31 |
| Tales of Arise |
Sony PS4 | Bandai Namco | Action and RPG & JRPG | Tales | 2021-12-31 |
